The 71 High Cut-Off Microdialysis Bolt Catheter is designed for implantation in brain tissue through the PTO 2L bolt kit from Raumedic or the IM3 Bolt Kit for 3 brain probes from Integra. The catheter has a 130 mm long shaft and a membrane length of 10 mm. The shaft has a reinforced stainless steel section measuring 16.5 mm in length. This reinforcement is located where the compression screw of the bolt is to be tightened.
The tip of the Catheter contains a gold tread, which makes it visible on a CT-scan in order to locate the exact position of the catheter in the brain.
The most important characteristic of this microdialysis catheter is the dialysing membrane that has pores big enough to allow diffusion of large molecules such as cytokines.
The 71 High Cut-Off Bolt Microdialysis Catheter is connected to a Microdialysis Pump. To avoid ultrafiltration of the dialysis membrane, the catheter should be perfused with Perfusion fluid CNS Dextran. The outlet tube extends to a holder for a microvial that collects the dialysis sample. The microdialysis samples can be analyzed in the ISCUSflex Microdialysis Analyzer for Glucose, Lactate, Pyruvate, Glycerol, Glutamate and Urea or sent to a clinical laboratory for analysis of large molecules such as cytokines.
Microdialysis shall not be used as the sole basis for diagnosis or therapy.
Intended Purpose
The Brain Microdialysis Catheter is intended to enable Microdialysis of the extracellular (interstitial) fluid of the brain tissue.