Bibliography on Cutaneous Microdialysis

If you would like to add a reference, please send the publication or fax/mail the reference to:
M Dialysis AB
Att: Katarina Åsberg
Box 5049, SE-121 05 Stockholm, Sweden
Tel +46-8-470 10 40 Fax +46-8-470 10 55
E-mail ka@mdialysis.se

Metabolome analyses of skin dialysate: Insights into skin interstitial fluid biomarkers. Oharazawa A, Maimaituxun G, Watanabe K, Nishiyasu T, Fujii N.J Dermatol Sci. 2024 Jun;114(3):141-147. doi: 10.1016/j.jdermsci.2024.04.001. Epub 2024 Apr 26.PMID: 38740531

Dermal microdialysis: A method to determine drug levels in the skin of patients with Post kala-azar dermal leishmaniasis (PKDL). Wijnant GJ, Moulik S, Chatterjee K, Das NK, de la Flor R, Van Bocxlaer K, Croft SL, Chatterjee M.Exp Parasitol. 2024 Feb;257:108687. doi: 10.1016/j.exppara.2023.108687. Epub 2023 Dec 17.PMID: 38114040

GH and IGF-1 in skin interstitial fluid and blood are associated with heat loss responses in exercising young adults. Maimaituxun G, Amano T, Kenny GP, Mündel T, Kajiki M, Tagawa K, Katagiri A, Tanabe Y, Watanabe K, Nishiyasu T, Kondo N, Fujii N.Eur J Appl Physiol. 2024 Mar 6. doi: 10.1007/s00421-024-05448-9. Online ahead of print.PMID: 38446190

Intravenous Cefazolin Achieves Sustained High Interstitial Concentrations in Open Lower Extremity Fractures. Bates TJ, Burgess MB, Garcia GR, Akers KS, Mangum LC, Lynch TB, Wenke JC, Pierrie SN.Clin Orthop Relat Res. 2023 Aug 22. doi: 10.1097/CORR.0000000000002808. Online ahead of print.

Effects of a mitochondrial-targeted ubiquinol on vascular function and exercise capacity in chronic kidney disease: a randomized controlled pilot study. Kirkman DL, Stock JM, Shenouda N, Bohmke NJ, Kim Y, Kidd J, Townsend RR, Edwards DG.Am J Physiol Renal Physiol. 2023 Oct 1;325(4):F448-F456. doi: 10.1152/ajprenal.00067.2023. Epub 2023 Aug 10.

Intradermal substance P as a challenge agent in healthy individuals. Ten Voorde W, Akinseye C, Abdisalaam I, Wind S, Klarenbeek N, Bergmans M, van Doorn M, Rissmann R, Kaur R, Hotee S, Foster K, Nair A, Fortunato L, Macphee C, Mole S, Baumann K, Brigandi R.Clin Transl Sci. 2023 Aug 7. doi: 10.1111/cts.13592. Online ahead of print.

Nitric oxide-mediated cutaneous microvascular function is not altered in middle-aged-to-older adults following mild SARS-CoV-2 infection: A pilot study. Dillon GA, Wolf ST, Williams AC, Kenney WL, Alexander LM.Physiol Rep. 2023 Jun;11(11):e15704. doi: 10.14814/phy2.15704.PMID: 37269174

Serum, interstitial and sweat ATP in humans exposed to heat stress: Insights into roles of ATP in the heat loss responses. Fujii N, Tanabe Y, Amano T, Watanabe K, Kondo N, Nishiyasu T, Kenny GP.Clin Physiol Funct Imaging. 2023 May 4. doi: 10.1111/cpf.12825. Online ahead of print

Endothelin A receptor inhibition increases nitric oxide-dependent vasodilation independent of superoxide in non-Hispanic Black young adults. Turner CG, Hayat MJ, Grosch C, Quyyumi AA, Otis JS, Wong BJ.J Appl Physiol (1985). 2023 Apr 1;134(4):891-899. doi: 10.1152/japplphysiol.00739.2022. Epub 2023 Mar 9.PMID: 36892887

Effects of biological sex and oral contraceptive pill use on cutaneous microvascular endothelial function and nitric oxide-dependent vasodilation in humans. Turner CG, Stanhewicz AE, Nielsen KE, Otis JS, Feresin RG, Wong BJ.J Appl Physiol (1985). 2023 Apr 1;134(4):858-867. doi: 10.1152/japplphysiol.00586.2022. Epub 2023 Mar 2.PMID: 36861674

Sex differences in microvascular function and arterial hemodynamics in nondialysis chronic kidney disease. Kirkman DL, Ramick MG, Muth BJ, Stock JM, Townsend RR, Edwards DG.Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1130-H1136. doi: 10.1152/ajpheart.00500.2022. Epub 2022 Oct 21.

Seven days of statin treatment improves nitric-oxide mediated endothelial-dependent cutaneous microvascular function in women with endometriosis. Dillon GA, Stanhewicz AE, Serviente C, Flores VA, Stachenfeld N, Alexander LM.Microvasc Res. 2022 Nov;144:104421. doi: 10.1016/j.mvr.2022.104421. Epub 2022 Aug 12.PMID: 35970408

Skin pigmentation is negatively associated with circulating vitamin D concentration and cutaneous microvascular endothelial function. Wolf ST, Dillon GA, Alexander LM, Jablonski NG, Kenney WL.Am J Physiol Heart Circ Physiol. 2022 Sep 1;323(3):490-498. doi: 10.1152/ajpheart.00309.2022. Epub 2022 Aug 5.PMID: 35930446

Oxidative stress contributes to reductions in microvascular endothelial- and nitric oxide-dependent dilation in women with a history of gestational diabetes. Stanhewicz AE, Schlarmann RL, Brustkern KM, Jalal DI.J Appl Physiol (1985). 2022 Aug 1;133(2):361-370. doi: 10.1152/japplphysiol.00189.2022. Epub 2022 Jul 7.

Influence of uncomplicated, controlled hypertension on local heat-induced vasodilation in nonglabrous skin across the body. McGarr GW, King KE, Akerman AP, Fujii N, Ruzicka M, Kenny GP.Am J Physiol Regul Integr Comp Physiol. 2022 Apr 1;322(4):R326-R335. doi: 10.1152/ajpregu.00282.2021. Epub 2022 Feb 16.PMID: 35170329

Nitric oxide-mediated cutaneous microvascular function is not altered in young adults following mild-to-moderate SARS CoV-2 infection. Dillon GA, Wolf ST, Alexander LM.Am J Physiol Heart Circ Physiol. 2022 Feb 1;322(2):H319-H327. doi: 10.1152/ajpheart.00602.2021. Epub 2022 Jan 7.

Contributions of endothelin-1 and l-arginine to blunted cutaneous microvascular function in young, black women. Akins JD, Richey RE, Campbell JC, Martin ZT, Olvera G, Brothers RM.Am J Physiol Heart Circ Physiol. 2022 Feb 1;322(2):H260-H268. doi: 10.1152/ajpheart.00457.2021. Epub 2021 Dec 17

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging. Kuzma BA, Pence IJ, Ho A, Evans CL.J Vis Exp. 2021 Nov 24;(177). doi: 10.3791/63264

Investigation of proteins important for microcirculation using in vivo microdialysis after glucose provocation: a proteomic study. Högstedt A, Farnebo S, Tesselaar E, Ghafouri B.Sci Rep. 2021 Sep 27;11(1):19093. doi: 10.1038/s41598-021-98672-8.

Autologous serum skin test reactions in chronic spontaneous urticaria differ from heterologous cell reactions.

Baumann K, Marcelino J, Skov PS, Santos MCP, Wyroslak I, Scheffel J, Altrichter S, Woetmann A, Costa C, Maurer M.J Eur Acad Dermatol Venereol. 2021 Jan 21. doi: 10.1111/jdv.17131. Online ahead of print.PMID: 33475206

Effects of short-term heat acclimation on whole-body heat exchange and local nitric oxide synthase- and cyclooxygenase-dependent heat loss responses in exercising older men.

Fujii N, McGarr GW, Notley SR, Boulay P, Sigal RJ, Amano T, Nishiyasu T, Poirier MP, Kenny GP.Exp Physiol. 2021 Feb;106(2):450-462. doi: 10.1113/EP089025. Epub 2020 Dec 28.PMID: 33347660

Sampling insulin in different tissue compartments using microdialysis: methodological aspects.

Högstedt A, Ghafouri B, Tesselaar E, Farnebo S.Sci Rep. 2020 Dec 15;10(1):21948. doi: 10.1038/s41598-020-78728-x.

TRPV4 channel blockade does not modulate skin vasodilation and sweating during hyperthermia or cutaneous post-occlusive reactive and thermal hyperemia.

Fujii N, Kenny GP, McGarr GW, Amano T, Honda Y, Kondo N, Nishiyasu T.Am J Physiol Regul Integr Comp Physiol. 2020 Oct 21. doi: 10.1152/ajpregu.00123.2020. Online ahead of print.

KCa channels are major contributors to ATP-induced cutaneous vasodilation in healthy older adults.

McGarr GW, Muia CM, Saci S, Fujii N, Kenny GP.Microvasc Res. 2020 Oct 12:104096. doi: 10.1016/j.mvr.2020.104096. Online ahead of print.PMID: 33058899

Four weeks of vitamin D supplementation improves nitric oxide-mediated microvascular function in college-aged African Americans.

Wolf ST, Jablonski NG, Ferguson SB, Alexander LM, Kenney WL.Am J Physiol Heart Circ Physiol. 2020 Oct 1;319(4):H906-H914. doi: 10.1152/ajpheart.00631.2020. Epub 2020 Aug 28.

AHA/ACC-defined stage 1 hypertensive adults do not display cutaneous microvascular endothelial dysfunction.

Dillon GA, Greaney JL, Shank S, Leuenberger UA, Alexander LM.Am J Physiol Heart Circ Physiol. 2020 Sep 1;319(3):H539-H546. doi: 10.1152/ajpheart.00179.2020. Epub 2020 Jul 31

Peripheral microvascular serotoninergic signaling is dysregulated in young adults with major depressive disorder.

Greaney JL, Dillon GA, Saunders EFH, Alexander LM.J Appl Physiol (1985). 2020 Jan 1;128(1):100-107. doi: 10.1152/japplphysiol.00603.2019. Epub 2019 Nov 21

Greater Daily Psychosocial Stress Exposure is Associated With Increased Norepinephrine-Induced Vasoconstriction in Young Adults.

Greaney JL, Surachman A, Saunders EFH, Alexander LM, Almeida DM.J Am Heart Assoc. 2020 May 5;9(9):e015697. doi: 10.1161/JAHA.119.015697. Epub 2020 Apr 28

Regional influence of nitric oxide on cutaneous vasodilatation and sweating during exercise-heat stress in young men.

Schmidt MD, McGarr GW, Muia CM, Fujii N, Amano T, Kenny GP.Exp Physiol. 2020 May;105(5):773-782. doi: 10.1113/EP088388. Epub 2020 Apr 20.

NO-mediated activation of KATP channels contributes to cutaneous thermal hyperemia in young adults.

Fujii N, McGarr GW, Kenny GP, Amano T, Honda Y, Kondo N, Nishiyasu T.Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R390-R398. doi:

Intradermal Administration of Atrial Natriuretic Peptide Attenuates Cutaneous Vasodilation but Not Sweating in Young Men during Exercise in the Heat.

McGarr GW, Fujii N, Muia CM, Nishiyasu T, Kenny GP.Skin Pharmacol Physiol. 2020;33(2):86-93. doi: 10.1159/000505300. Epub 2020 Jan 31

The Skin Reservoir Model: A Tool for Evaluating Microdialysis Sampling of Large Biomarkers from Human Skin.

Baumann K, Falkencrone S, Knudsen NP, Woetmann A, Dabelsteen S, Skov PS.Acta Derm Venereol. 2020 Jan 7;100(1):adv00008. doi: 10.2340/00015555-3356

Intradermal Administration of Atrial Natriuretic Peptide Attenuates Cutaneous Vasodilation but Not Sweating in Young Men during Exercise in the Heat.

McGarr GW, Fujii N, Muia CM, Nishiyasu T, Kenny GP.Skin Pharmacol Physiol. 2020;33(2):86-93. doi: 10.1159/000505300. Epub 2020 Jan 31

Peripheral Microvascular Serotoninergic Signaling is Dysregulated in Young Adults with Major Depressive Disorder.

Greaney JL, Dillon GA, Saunders EFH, M Alexander L.
J Appl Physiol (1985). 2019 Nov 21. doi: 10.1152/japplphysiol.00603.2019. [Epub ahead of print]

Reduced central sympathetic activity in Parkinson’s disease.

Krämer HH, Lautenschläger G, de Azevedo M, Doppler K, Schänzer A, Best C, Oertel WH, Reuter I, Sommer C, Birklein F.Brain Behav. 2019 Dec;9(12):e01463. doi: 10.1002/brb3.1463. Epub 2019 Nov 5

Acute consumption of flavanol-rich cocoa beverage improves attenuated cutaneous microvascular function in healthy young African Americans.

Kim K, Brothers RM.Microvasc Res. 2020 Mar;128:103931. doi: 10.1016/j.mvr.2019.103931. Epub 2019 Oct 22

Sunscreen or simulated sweat minimizes the impact of acute ultraviolet radiation on cutaneous microvascular function in healthy humans.

Wolf ST, Berry CW, Stanhewicz AE, Kenney LE, Ferguson SB, Kenney WL.
Exp Physiol. 2019 Jul;104(7):1136-1146. doi: 10.1113/EP087688. Epub 2019 May 9.

Skin microdialysis: methods, applications and future opportunities-an EAACI position paper. Baumann KY, Church MK, Clough GF, Quist SR, Schmelz M, Skov PS, Anderson CD, Tannert LK, Giménez-Arnau AM, Frischbutter S, Scheffel J, Maurer M.Clin Transl Allergy. 2019 Apr 10;9:24. doi: 10.1186/s13601-019-0262-y. eCollection 201

Age-related differences in the cutaneous vascular response to exogenous angiotensin II. Lang JA, Krajek ACAm J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H516-H521. doi: 10.1152/ajpheart.00509.2018. Epub 2018 Nov 30

Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.

Gan LM, Lagerström-Fermér M, Carlsson LG, Arfvidsson C, Egnell AC, Rudvik A, Kjaer M, Collén A, Thompson JD, Joyal J, Chialda L, Koernicke T, Fuhr R, Chien KR, Fritsche-Danielson R.
Nat Commun. 2019 Feb 20;10(1):871. doi: 10.1038/s41467-019-08852-4.
PMID: 30787295 Free PMC Article

Oxidative Stress Contributes to Microvascular Endothelial Dysfunction in Men and Women With Major Depressive Disorder.

Greaney JL, Saunders EFH, Santhanam L, Alexander LM.
Circ Res. 2019 Feb 15;124(4):564-574. doi: 10.1161/CIRCRESAHA.118.313764.

GSK2646264, a spleen tyrosine kinase inhibitor attenuates the release of histamine in ex vivo human skin.

Dickson M, Ramirez-Molina C, Falkencrone S, Skov PS, Hooper-Greenhill E, Barker M.
Br J Pharmacol. 2019 Feb 8. doi: 10.1111/bph.14610. [Epub ahead of print]

Ageing attenuates muscarinic-mediated sweating differently in men and women with no effect on nicotinic-mediated sweating.

Fujii N, McGarr GW, Nishiyasu T, Sigal RJ, Boulay P, Kenny GP.
Exp Dermatol. 2019 Jan 10. doi: 10.1111/exd.13878. [Epub ahead of print]

Seven consecutive days of remote ischaemic preconditioning improves cutaneous vasodilatory capacity in young adults.

Lang JA, Kim J, Franke WD, Vianna LC.
J Physiol. 2019 Feb;597(3):757-765. doi: 10.1113/JP277185. Epub 2018 Dec 17.

Sex differences in the mechanisms mediating blunted cutaneous microvascular function in young black men and women.

Patik JC, Curtis BM, Nasirian A, Vranish JR, Fadel PJ, Brothers RM.
Am J Physiol Heart Circ Physiol. 2018 Aug 3. doi: 10.1152/ajpheart.00142.2018.

Qualitative and quantitative analysis of lateral diffusion of drugs in human skin.

Nguyen HX, Puri A, Bhattaccharjee SA, Banga AK.
Int J Pharm. 2018 Jun 10

Cytokine and Chemokine Recovery Is Increased by Colloid Perfusates during Dermal Microdialysis.

Quist SR, Kirbs C, Kloft C, Gollnick HP.
Materials (Basel). 2018 Apr 27

The contribution of noradrenergic nerves to the vasoconstrictor response during local cooling of leg and forearm skin in humans.

Al-Horani RA, Mohammad M.
Gen Physiol Biophys. 2018 Jan;37(1):33-40. doi: 10.4149/gpb_2017021.

Tempol augments the blunted cutaneous microvascular thermal reactivity in healthy young African Americans.

Hurr C, Patik JC, Kim K, Christmas KM, Brothers RM.
Exp Physiol. 2017 Dec 22. doi: 10.1113/EP086776. [Epub ahead of print]

Is a positive intracutaneous test induced by penicillin mediated by histamine? A cutaneous microdialysis study in penicillin-allergic patients.

Tannert LK, Falkencrone S, Mortz CG, Bindslev-Jensen C, Skov PS.
Clin Transl Allergy. 2017 Nov 17;7:40. doi: 10.1186/s13601-017-0179-2. eCollection 2017.

Voltage-gated potassium channels and NOS contribute to a sustained cutaneous vasodilation elicited by local heating in an interactive manner in young adults.

Fujii N, Halili L, Nishiyasu T, Kenny GP.
Microvasc Res. 2017 Dec 13;117:22-27. doi: 10.1016/j.mvr.2017.12.001

Acute lysyl oxidase inhibition alters microvascular function in normotensive, but not hypertensive, men and women.

Craighead DH, Wang H, Santhanam L, Alexander LM.
Am J Physiol Heart Circ Physiol. 2017 Nov 22:ajpheart005212017. doi: 10.1152/ajpheart.00521.2017.

Oxidative stress does not influence local sweat rate during high-intensity exercise.

Meade RD, Fujii N, Poirier MP, Boulay P, Sigal RJ, Kenny GP.
Exp Physiol. 2017 Nov 19. doi: 10.1113/EP086746

The role of mitochondria derived reactive oxygen species in microvascular dysfunction in chronic kudney disease.

Kirkman DL, Muth BJ, Ramick MG, Townsend RR, Edwards DG.
Am J Physiol Renal Physiol. 2017 Nov 8:ajprenal003212017. doi: 10.1152/ajprenal.00321.2017

Cutaneous reactive hyperaemia is unaltered by dietary nitrate supplementation in healthy humans.

Wong BJ, Keen JT, Levitt EL.
Clin Physiol Funct Imaging. 2017 Oct 29. doi: 10.1111/cpf.12478.

Intradermal administration of atrial natriuretic peptide has no effect on sweating and cutaneous vasodilator responses in young male adults.

Fujii N, McNeely BD, Nishiyasu T, Kenny GP.
Temperature (Austin). 2017 Oct 9;4(4):406-413. doi: 10.1080/23328940.2017.1356433.

The Effect of Being Aerobically Active vs. Inactive on Cutaneous Vascular Conductance during Local Heat Stress in an Older Population.

Mitchell UH, Burton S, Gordon C, Mack GW.
Front Physiol. 2017 Oct 31;8:859. doi: 10.3389/fphys.2017.00859. eCollection 2017

Skin Blood Flow and Vascular Endothelium Function in Uremia.

Smogorzewski MJ.
J Ren Nutr. 2017 Nov;27(6):465-469. doi: 10.1053/j.jrn.2017.04.012.

Effect of sympathetic nerve blockade on low-frequency oscillations of forearm and leg skin blood flow in healthy humans.

Hodges GJ, Mallette MM, Martin ZT, Del Pozzi AT.
Microcirculation (New York, N.Y. : 1994). 2017 Jun 19. doi: 10.1111/micc.12388. [Epub ahead of print]

Cutaneous Vasodilation during Local Heating: Role of Local Cutaneous Thermosensation.

Mack GW, Foote KM, Nelson WB.
Front Physiol. 2016 Dec 20;7:622. doi: 10.3389/fphys.2016.00622. eCollection 2016.

Effect of hypohydration on postsynaptic cutaneous vasodilation and sweating in healthy men.

Tucker MA, Six A, Moyen NE, Satterfield AZ, Ganio MS.
Am J Physiol Regul Integr Comp Physiol. 2017 May 1;312(5):R637-R642. doi: 10.1152/ajpregu.00525.2016. Epub 2017 Feb 15.

Skin glucose metabolism and microvascular blood flow during local insulin delivery and after an oral glucose load.

Iredahl F, Högstedt A, Henricson J, Sjöberg F, Tesselaar E, Farnebo S.
Microcirculation (New York, N.Y. : 1994). 2016 Sep 28. doi: 10.1111/micc.12325

K+ channel mechanisms underlying cholinergic cutaneous vasodilation and sweating in young humans: roles of KCa, KATP, and KV channels?

Fujii N, Louie JC, McNeely BD, Zhang SY, Tran MA, Kenny GP.
Am J Physiol Regul Integr Comp Physiol. 2016 Jul 20:ajpregu.00249.2016. doi: 10.1152/ajpregu.00249.2016. [Epub ahead of print]

Dairy cheese consumption ameliorates single-meal sodium-induced cutaneous microvascular dysfunction by reducing ascorbate-sensitive oxidants in healthy older adults.

Stanhewicz AE, Alba BK, Kenney WL, Alexander LM.
Br J Nutr. 2016 Aug;116(4):658-65. doi: 10.1017/S0007114516002579. Epub 2016 Jul 1.

Passive heat therapy improves cutaneous microvascular function in sedentary humans via improved nitric oxide-dependent dilation.

Brunt VE, Eymann TM, Francisco MA, Howard MJ, Minson CT.
J Appl Physiol (1985). 2016 Jul 14:jap.00424.2016. doi: 10.1152/japplphysiol.00424.2016. [Epub ahead of print]

Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivo human skin – assessment by intradermal microdialysis and extraction from the different skin layers.

Döge N, Hönzke S, Schumacher F, Balzus B, Colombo M, Hadam S, Rancan F, Blume-Peytavi U, Schäfer-Korting M, Schindler A, Rühl E, Skov PS, Church MK, Hedtrich S, Kleuser B, Bodmeier R, Vogt A.
J Control Release. 2016 Jul 6. pii: S0168-3659(16)30434-5. doi: 10.1016/j.jconrel.2016.07.009. [Epub ahead of print]

Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin.
Schlereth T, Schukraft J, Krämer-Best HH, Geber C, Ackermann T, Birklein F.

Neuropeptides. 2016 Jun 18. pii: S0143-4179(16)30024-5. doi: 10.1016/j.npep.2016.06.001. [Epub ahead of print]

Acute dairy milk ingestion does not improve nitric oxide-dependent vasodilation in the cutaneous microcirculation.

Alba BK, Stanhewicz AE, Kenney WL, Alexander LM. Br J Nutr. 2016 May 16

Post Junctional Sudomotor and Cutaneous Vascular Responses in Noninjured Skin Following Heat Acclimation in Burn Survivors.

Pearson J, Ganio MS, Schlader ZJ, Lucas RA, Gagnon D, Rivas E, Davis SL, Kowalske KJ, Crandall CG.
J Burn Care Res. 2016 Jun 28. [Epub ahead of print]

Sustained cutaneous vasoconstriction during and following cyrotherapy treatment: Role of oxidative stress and Rho kinase.

Christmas KM, Patik JC, Khoshnevis S, Diller KR, Brothers RM.
Microvasc Res. 2016 Jul;106:96-100. doi: 10.1016/j.mvr.2016.04.005. Epub 2016 Apr 14

Cutaneous blood flow during intradermal NO administration in young and older adults: roles for calcium-activated potassium channels and cyclooxygenase?

Fujii N, Meade RD, Minson CT, Brunt VE, Boulay P, Sigal RJ, Kenny GP.
Am J Physiol Regul Integr Comp Physiol. 2016 Apr 6

Kinetic Profile of Inflammation Markers in Human Skin In Vivo Following Exposure to Ultraviolet B Indicates Synchronic Release of Cytokines and Prostanoids.

Quist SR, Wiswedel I, Quist J, Gollnick HP.
Acta Derm Venereol. 2016 Mar 17. doi: 10.2340/00015555-2406. [Epub ahead of print]

Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis.

Quist SR, Wiswedel I, Doering I, Quist J, Gollnick HP.
Acta Derm Venereol. 2016 Feb 25. doi: 10.2340/00015555-2383. [Epub ahead of print

Endothelial-derived hyperpolarization contributes to acetylcholine-mediated vasodilation in human skin in a dose-dependent manner.

Brunt VE, Fujii N, Minson CT.
J Appl Physiol (1985). 2015 Sep 17:jap.00201.2015. doi: 10.1152/japplphysiol.00201.2015. [Epub ahead of print

Intradermal administration of ATP augments methacholine-induced cutaneous vasodilation but not sweating in young males and females.

Fujii N, Halili L, Singh MS, Meade RD, Kenny GP.
Am J Physiol Regul Integr Comp Physiol. 2015 Aug 19:ajpregu.00261.2015. doi: 10.1152/ajpregu.00261.2015. [Epub ahead of print]

Evidence for a functional vasodilatory role for hydrogen sulfide in the human cutaneous microvasculature.

Kutz JL, Greaney JL, Santhanam L, Alexander LM.
J Physiol. 2015 Jan 30. doi: 10.1113/JP270054.

Acute hyperglycaemia does not alter nitric oxide-mediated microvascular function in the skin of adolescents with type 1 diabetes.

Naylor LH, Yusof NM, Paramalingam N, Jones TW, Davis EA, Green DJ.
Eur J Appl Physiol. 2014 Feb;114(2):435-41. doi: 10.1007/s00421-013-2785-6. Epub 2013 Dec 13.

The regional differences in the contribution of nitric oxide synthase to skin blood flow at forearm and lower leg sites in response to local skin warming.

Del Pozzi AT, Carter SJ, Collins AB, Hodges GJ.

Microvasc Res. 2013 Nov;90:106-11.

Iontophoresis successfully delivers dexamethasone sodium phosphate to dermis as measured by microdialysis.

Joshi A, Stagni G, Cleary A, Patel K, Weiss DS, Hagins M.
J Pharm Sci. 2014 Jan;103(1):191-6. doi: 10.1002/jps.23771. Epub 2013 Nov 6

Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans.

Smith CJ, Santhanam L, Alexander LM.
Microvasc Res. 2013 Feb 26. doi:pii: S0026-2862(13)00025-3. 10.1016/j.mvr.2013.02.005

Regional Relation between Skin Blood Flow and Sweating to Passive Heating and Local Administration of Acetylcholine in Young, Healthy Humans.

Smith CJ, Kenney WL, Alexander LM.
Am J Physiol Regul Integr Comp Physiol. 2013 Feb 6

No direct role for A1/A2 Adenosine Receptor Activation to reflex cutaneous vasodilatation during whole body heat stress in humans.

Fieger SM, Wong BJ.
Acta Physiol (Oxf). 2012 Feb 22. doi: 10.1111/j.1748-1716.2012.02426.x. [Epub ahead of print

Oral vitamin C enhances the adrenergic vasoconstrictor response to local cooling in human skin.

Yamazaki F.
J Appl Physiol. 2012 Mar 1. [Epub ahead of print]

Cutaneous Microdialysis: Cytokine Evidence for Altered Innate Reactivity in the Skin of Psoriasis Patients?

Sjögren F, Davidsson K, Sjöström M, Anderson CD.
AAPS J. 2012 Feb 29. [Epub ahead of print]

A human vascular model based on microdialysis for the assessment of the vasoconstrictive dose response effects of noradrenaline and vasopressin in skin.

Folkesson KT, Samuelsson A, Tesselaar E, Dahlström B, Sjöberg F.
Microcirculation (New York, N.Y. : 1994). 2012 Feb 14. doi: 10.1111/j.1549-8719.2012.00170.x. [Epub ahead of print

Reactive Oxygen Species (ROS) from NADPH and Xanthine Oxidase Modulate the Cutaneous Local Heating Response in Healthy Humans

Medow MS, Bamji N, Clarke D, Ocon AJ, Stewart JM.
J Appl Physiol. 2011 Mar 24. [Epub ahead of print

Microdialysis documents changes in the micromilieu of psoriatic plaques under continuous systemic therapy.

Salgo R, Thaçi D, Boehncke S, Diehl S, Hofmann M, Boehncke WH.
Exp Dermatol. 2011 Feb;20(2):130-3. doi: 10.1111/j.1600-0625.2010.01212.x.

A Modified in vivo Flow Variation Technique of Microdialysis for Sampling Uremic Toxins in the Subcutaneous Interstitial Compartment.

Ebah L, Brenchley P, Coupes B, Mitra S.
Blood Purif. 2011 Mar 2;32(2):96-103. [Epub ahead of print]

Modest but increased penetration through damaged skin: an overview of the in vivo human model.
Gattu S, Maibach HI.

Skin Pharmacol Physiol. 2011;24(1):2-9. Epub 2010 Jun 30

Are cutaneous microdialysis cytokine findings supported by end-point biopsy immunohistochemistry findings?

Sjögren F, Anderson C D.
AAPS Journal online 22 October 2010 DOI:10.1208/s12248-010-9235-8

No effect of systemic isocapnic hypoxia on ?-adrenergic vasoconstrictor responsiveness in human skin.

Simmons GH, Fieger SM, Wong BJ, Minson CT, Halliwill JR.
Acta Physiol (Oxf). 2010 Oct 14. doi: 10.1111/j.1748-1716.2010.02193.x. [Epub ahead of print]

Transient receptor potential vanilloid type-1 (trpv-1) channels contribute to cutaneous thermal hyperaemia in humans.

Wong BJ, Fieger SM.
J Physiol. 2010 Aug 31. [Epub ahead of print]

Skin Blood Flow and Local Temperature Independently Modify Sweat Rate During Passive Heat Stress in Humans.

Wingo JE, Low DA, Keller DM, Brothers RM, Shibasaki M, Crandall CG.
J Appl Physiol. 2010 Aug 12. [Epub ahead of print]

Adenosine receptor inhibition with theophylline attenuates the skin blood flow response to local heating in humans.

Fieger SM, Wong BJ.
Exp Physiol. 2010 Sep;95(9):946-54. Epub 2010 Jun 18

Experimental thermal lesions induce beta-thromboglobulin release from activated platelets.

Blunk JA, Sauerstein K, Schmelz M.
Eur J Pain. 2010 May 24. [Epub ahead of print]

VIP/PACAP Receptor Mediation of Cutaneous Active Vasodilation During Heat Stress in Humans.

Kellogg DL Jr, Zhao JL, Wu Y, Johnson JM.
J Appl Physiol. 2010 Apr 15. [Epub ahead of print]

Systemic low-dose aspirin and clopidogrel independently attenuate reflex cutaneous vasodilation in middle-aged humans.

Holowatz LA, Jennings JD, Lang JA, Kenney WL.
J Appl Physiol. 2010 Jun;108(6):1575-81. Epub 2010 Apr 1

Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human
forearm skin.

Leis S, Meyer N, Bickel A, Schick CH, Krüger S, Schmelz M, Birklein F.
Pain Med. 2010 May;11(5):774-80. Epub 2010 Mar 1

Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction.

Lang JA, Holowatz LA, Kenney WL.
J Physiol. 2010 Apr 15;588(Pt 8):1361-8. Epub 2010 Feb 22

Nitric oxide synthase inhibition attenuates cutaneous vasodilation during postmenopausal hot flash episodes.

Hubing KA, Wingo JE, Brothers RM, Del Coso J, Low DA, Crandall CG.
Menopause. 2010 May 24. [Epub ahead of print]

Microdialysis Sampling for Investigations of Bioavailability and Bioequivalence of Topically Administered Drugs: Current State and Future Perspectives.

Holmgaard R, Nielsen JB, Benfeldt E.
Skin Pharmacol Physiol. 2010 May 18;23(5):225-243. [Epub ahead of print]

Intradermal Administration of ATP Does Not Mitigate Tyramine-Stimulated Vasoconstriction in Human Skin.

Wingo JE, Brothers RM, Del Coso J, Crandall CG.
Am J Physiol Regul Integr Comp Physiol. 2010 Mar 17. [Epub ahead of print]

Thoracoscopic Sympathectomy at the T2 or T3 Level Facilitates Bradykinin-Induced Protein Extravasation in Human Forearm Skin.

Leis S, Meyer N, Bickel A, Schick CH, Krüger S, Schmelz M, Birklein F.
Pain Med. 2010 Mar 1. [Epub ahead of print]

Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction.

Lang JA, Holowatz LA, Kenney WL.
J Physiol. 2010 Feb 22. [Epub ahead of print]

Local ascorbate administration inhibits the adrenergic vasoconstrictor response to local cooling in the human skin.

Yamazaki F.
J Appl Physiol. 2010 Feb;108(2):328-33. Epub 2009 Dec 10.

Mechanical but not painful electrical stimuli trigger TNF alpha release in human skin.

Eberle T, Doganci B, Krämer H, Fechir M, Wagner I, Sommer C, Birklein F.
Exp Neurol. 2010 Jan;221(1):246-50. Epub 2009 Nov 18